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Abstract #3609

Assessments of Flow Velocity Changes by Phase-Contrast MRI Near Acoustic Radiation Force Aggregated Bubbles

Zhe-Wei Wu1, Wu Chen-Hua2, Hsu Po-Hong3, Hao-Li Liu3, Yeh Chic-Kuang2, and Peng Hsu-Hsia2

1Biomedical Engineering and Environmental Sciences, Nation Tsing Hua University, Hsinchu, Taiwan, 2Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 3Electrical Engineering, Chang-Gung University, Taoyuan, Taiwan

The aim of this study was to real-time assess flow velocity changes in the neighboring pixels of acoustic radiation force (ARF) aggregated bubbles by using phase-contrast MRI (PC-MRI). The flow velocity increased with the increase of microbubbles (MBs) concentrations, which might be attributed to the increase of aggregated bubbles size, narrowing the chamber diameter and thus presenting higher flow velocity. In conclusion, we verified the feasibility of using PC-MRI to assess flow velocity changes on pixels near ARF aggregated bubbles. In the future, a systematic investigation shall be conducted to comprehend the association between bubble size and the flow velocity.

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