Abstract #3853

Iron measurements by quantitative MRI-R2* at 3.0 and 1.5 T

Jin Yamamura¹, Sarah Keller¹, Regine Grosse², Bjoern Schoennagel¹, Peter Nielsen³, Zhiyue Jerry Wang⁴, Joachim Graessner⁵, Hendrick Kooijman⁶, Gerhard Adam¹, and Roland Fischer^3,7

¹Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, ²Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, ³Biochemistry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, ⁴Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, ⁵Siemens Healthcare AG, Hamburg, Germany, ⁶Philips Medical Care, Hamburg, Germany, ⁷Radiology, Children’s Hospital & Research Center Oakland, Oakland, CA, United States

We are investigating the suitability of a 3.0 T imager for iron measurements over the whole range of possible iron concentrations in the liver and spleen iron. For liver iron measurements in severely overloaded patients with LIC > 2400 µg/gliver or > 15 mg/gdry weight, 1.5 Tesla imagers are better suited than 3.0 Tesla systems.

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