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Abstract #3855

Agreement between MRE-estimated liver stiffness using 2D GRE and 2D SE-EPI pulse sequences at 3T

Adrija Mamidipalli1, Jonathan Hooker1, Nikolaus Szevrenyi1, Alexandra Schlein1, William Hauffe1, Tanya Wolfson2, Gavin Hamilton1, Michael Middleton1, and Claude Sirlin1

1Liver Imaging Group, UCSD, San Diego, CA, United States, 2Computational and Applied Statistics Laboratory, San Diego Supercomputer, UCSD, San Diego, CA, United States

In this study, agreement between MRE-estimated liver stiffness using 2D GRE and SE-EPI pulse sequences at 3T was examined in 30 adults with histology-confirmed nonalcoholic fatty liver disease (NAFLD) enrolled in a research registry. Results show that liver stiffness values obtained from both the sequences agree closely across a range of liver stiffness values for adults with NAFLD, although agreement tends to diverge at higher stiffness values. Differences at higher liver stiffness values were not explained by differences in image wave quality.

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