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Abstract #3900

Estimation of Oxygen Saturation in Renal Blood Using Intravoxel Incoherent Motion (IVIM) Imaging by FLAIR DWI

Tatsuo Nagasaka1, Hideki Ota2, and Hajime Tamura3

1Radiology, Tohoku University Hospital, Sendai, Japan, 2Diagnostic Radiology, Tohoku University Graduate School of Medicine, Sendai, Japan, 3Graduate School of Medicine, Tohoku University, Sendai, Japan

We aimed to apply IVIM imaging to estimate blood oxygen saturation in kidneys with extraction of glomerular filtrate fraction by using fluid-attenuated inversion recovery diffusion-weighted imaging (FLAIR DWI). A 3-compartment model (renal tissue, blood and water) was considered for the estimation. Combination of DWI and FLAIR DWI provided renal tissue T1. Images were acquired with two TEs to provide blood T2 which allows for estimation of blood oxygen saturation. Our model generated estimation of glomerular filtrate fraction, blood R2 and blood oxygen saturation. FLAIR DWI has a potential to estimate blood oxygen saturation with extracting glomerular filtrates fractions in kidneys.

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