Estimation of Oxygen Saturation in Renal Blood Using Intravoxel Incoherent Motion (IVIM) Imaging by FLAIR DWI
Tatsuo Nagasaka1, Hideki Ota2, and Hajime Tamura3
1Radiology, Tohoku University Hospital, Sendai, Japan, 2Diagnostic Radiology, Tohoku University Graduate School of Medicine, Sendai, Japan, 3Graduate School of Medicine, Tohoku University, Sendai, Japan
We aimed
to apply IVIM imaging to estimate blood oxygen saturation in kidneys with extraction of glomerular filtrate fraction by using fluid-attenuated
inversion recovery diffusion-weighted imaging (FLAIR DWI). A 3-compartment
model (renal tissue, blood and water) was considered for the estimation. Combination
of DWI and FLAIR DWI provided renal tissue T1. Images were acquired
with two TEs to provide blood T2 which allows for estimation of
blood oxygen saturation. Our model generated estimation
of glomerular filtrate fraction, blood R2 and blood oxygen
saturation. FLAIR DWI has a potential to estimate blood oxygen saturation with
extracting glomerular filtrates fractions in kidneys.
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