Abstract #3924

Assessment of Fat Accumulation and Mobilization during obesity and weight-loss Interventions in Rodents

Bhanu Prakash KN¹, Venkatesh Gopalan¹, Swee Shean Lee¹, and Sendhil Velan S^1,2

¹Laboratory of Metabolic Imaging, Singapore Bioimaging Consortium, Singapore, Singapore, ²Singapore Institute for Clinical Sciences, Singapore, Singapore

Quantification of adipose tissue distribution within the abdomen is fundamental for investigations in obesity and diabetes. Distribution of fat within the body, and its accumulation in the abdominal cavity, exert different physiologic effects based on their anatomical location. Calorie-restriction and exercise interventions improve obesity risk factors. Fat accumulation and mobilization can vary depending on the type and quality of fat in different locations. We have investigated the quantitative changes in fat volumes at different positions in the abdomen in diet induced obese rats.

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