Abstract #3930

Water-Fat MRI Detects Increased Brown Adipose Tissue Volume In Anticipation of Hibernation in Ground Squirrels

Amanda D MacCannell¹, Kevin J Sinclair², Lanette J Friesen-Waldner², Charles A McKenzie², and James F Staples¹

¹Biology, Western University, London, ON, Canada, ²Medical Biophysics, Western University, London, ON, Canada

During winter, brown adipose tissue (BAT) is the primary source of heat production in hibernating animals. White adipose tissue volumes increase and BAT-specific genes are upregulated in autumn even when temperatures are warm, but the rhythm of changes in BAT volume is unknown. Water-fat MRI was used to measure total BAT volume in hibernating squirrels two months after arousing from hibernation in spring and again at 18 days following the first MRI scan. BAT volumes increased significantly in this 20 day time period.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.