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Abstract #3943

A Beating Heart Simulation for Sequence Optimization of Sodium MRI

Simon Konstandin1 and Matthias Günther1,2

1MR-Imaging and Spectroscopy, University of Bremen, Bremen, Germany, 2Fraunhofer MEVIS, Bremen, Germany

Sodium MRI can act as a biomarker for heart tissue viability. However, several aspects (blurring behavior of non-Cartesian ultra-short echo time sequences, blurring because of heart motion, small myocardial infarction (MI) regions) complicate MI detection due to resolution reasons. Optimal sequence parameters are difficult to find since many subject parameters (e.g., relaxation times, heart motion) must be considered. The presented simulation model of a beating heart can be used to optimize sequence parameters, among other things, for better visualization of MI and can be adapted to any kind of motion and to different subject/physiological parameters.

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