Abstract #3991

Using partially suppressed water signal to improve J-edited proton MRS

Zhengchao Dong^1,2, Joshua Kantrowitz^1,2, and Hong Wang^1,3

¹Columbia University, New York, NY, United States, ²New York State Psychiatric Institute, New York, NY, United States, ³Tianjin University, Tianjin, China, People's Republic of

Magnetic field drift and subject motion during J-editing proton MRS scan will not only cause frequency and phase drifts in the spectrum but also alter the linewidth and lineshape. When the linewidths/shapes of edit-on and edit-off spectra do not match, the J-difference spectrum will have residue of Cr peaks; even when edit-on/off spectra match each other, the linebroadening and distortion will deteriorate the quality of the difference spectrum. In this study, we used the partially suppressed water signals to match and to transform the edit-on and edit-off spectra so as to improve the quality of the J-edited spectrum.

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