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Abstract #3993

Post acquisition frequency correction in GABA editing

Jan Willem van der Veen1, Stefano Marenco2, Karen Berman2, and Jun Shen1

1Magnetic Resonance Spectroacopy Core, NIH, NIMH, Bethesda, MD, United States, 2NIH,NIMH,CTNB, Bethesda, MD, United States

Patient motion and magnetic field drift may shift the frequency of the GABA editing pulse relative to that of metabolites. Using the frequency location of the residual water we corrected for changes caused by frequency variations by using averaged reference signals simulated at specific editing frequency offsets. Our analysis also showed that GABA editing with a top-hat editing pulse is highly robust in the presence of frequency variations.

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