Abstract #4087

Reproducibility of Cerebral Blood Flow Measurements Across MR Systems: A Matter of Magnet Geometry

Bogdan G Mitrea¹, Ralf B Loeffler¹, Ruitian Song¹, and Claudia M Hillenbrand¹

¹Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, TN, United States

For longitudinal investigations reproducibility and accuracy of ASL measurements are of essence. The purpose of this study is to investigate how magnet design and labeling position within the magnet impact CBF quantification. Our results indicate that CBF values are not always reproducible in our ultra-short wide bore scanner. Great variability may be introduced by the actual position of the labeling slice with respect to the magnet isocenter. The exact cause of this difference requires further investigation. However, positioning the labeling slice in isocenter provided a simple solution to overcome this issue and to measure reproducible CBF values.

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