Abstract #4095

Evaluation of Cerebral Venous Oxygen Saturation in Patients with Long-Term Haemodialysis using Susceptibility Mapping

Chao Chai¹, Linlin Fan², Chao Zuo³, Mengjie Zhang³, Lei Liu³, Zhiqiang Chu⁴, Tianyi Qian⁵, E Mark Haacke⁶, Shuang Xia³, and Wen Shen³

¹Department of Radiology, Tianjin First Central Hospital, Tianjin Medical University First Central Clinical college, Tianjin, China, People's Republic of, ²Department of Prophylactic Inoculation, Tianjin First Central Hospital, Tianjin Medical University First Central Clinical College, Tianjin, China, People's Republic of, ³Department of Radiology, Tianjin First Central Hospital, Tianjin Medical University First Central Clinical College, Tianjin, China, People's Republic of, ⁴Department of Haemodialysis, Tianjin First Central Hospital, Tianjin Medical University First Central Clinical college, Tianjin, China, People's Republic of, ⁵MR Collaboration NE Asia, Siemens Healthcare, Beijing, China, People's Republic of, ⁶Department of Radiology, Wayne State University, Detroit, MI, United States

The aim of this study was to explore cerebral venous oxygen saturation changes in long-term hemodialysis (HD) patients using susceptibility mapping (SWIM). SWIM was reconstructed from phase data of SWI and used to measure the susceptibility of cerebral veins in HD patients and healthy controls respectively. The results suggested that SWIM was a feasible and reliable method to measure the venous oxygen saturation. It can show the decrease of CMRO₂ in HD patients and the susceptibility value of the left cerebral cortical vein is positively correlated with MMSE scores.

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