Abstract #4171

Whole-brain volume alteration and its correlation with anxiety severity in patients with obsessive compulsive disorder and generalized anxiety disorder

Gwang-Won Kim¹, Chung-Man Moon¹, Tae-Hoon Kim¹, and Gwang-Woo Jeong^1,2

¹Research Institute of Medical Imaging, Chonnam National University Medical School, Gwang-ju, Korea, Republic of, ²Department of Radiology, Chonnam National University Medical School, Gwang-ju, Korea, Republic of

Obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD) are associated with abnormalities in the processing and regulation of anxiety. The purpose of this study was to evaluate gray matter (GM) and white matter (WM) volume alterations over whole-brain structures in healthy controls vs. patients with OCD vs. GAD using voxel-based morphometry (VBM), and further to assess the correlations of the GM and WM volume variations with the scores for anxiety severity in OCD and GAD.

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