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Abstract #4175

Slip interface imaging: a novel MR-elastography based imaging method for assessing the surgical plane of cleavage in meningiomas

Ziying Yin1, Kevin J. Glaser1, Armando Manduca2, Jamie J. Van Gompel3, Arvin Arani1, Joshua D. Hughes3, Anthony Romano4, Richard L. Ehman1, and John Huston III1

1Radiology, Mayo Clinic, Rochester, MN, United States, 2Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States, 3Neurosurgery, Mayo Clinic, Rochester, MN, United States, 4Naval Research Laboratory, Washington, WA, United States

The preoperative assessment of the surgical cleavage plane at the tumor-brain interface in meningiomas is important for surgical planning. A recently developed slip interface imaging (SII) technique is uniquely capable of directly assessing the degree of tumor adherence at the tumor-brain interface. In this study, SII was applied to assess the surgical cleavage plane between the tumor and the underlying brain in meningiomas. The correlation between the SII results and the surgical plane of cleavage was statistically significant (p=0.0014). The presence of a complete slip interface suggests the tumor can be removed using a dissection plane outside the pia mater.

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