Abstract #4385

Amide Proton Transfer-Weighted MR Imaging Signal as Predictor of Non Thrombolysis Treatment Efficiency for Stroke

Chunmei Li¹, Guodong Song¹, Yuhui Chen¹, Xuna Zhao², Jinyuan Zhou², and Min Chen¹

¹Beijing Hospital, Beijing, China, People's Republic of, ²Johns Hopkins University, Baltimore, MD, United States

This study is to evaluate the longitudinal Amide Proton Transfer-weighted (APTw) signal changes in patients with stroke after treatment. APT weighted images of stroke patients was acquired, including non-treatment and post treatment. 91.7% patients (22/24) showed gradual increased APT values with the extension of time, accompanied with the clinical symptoms improvement. The other 2 patients (8.3%) showed further decreased APT values in the second scan (the first scan after treatment), accompanied with the clinical symptoms aggravation. The increase of APT weighted signal may indicate the improvement of clinical symptoms while the decrease may indicate the aggravating of clinical symptoms.

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