Abstract #4390

In vivo T1 mapping of the spinal cord using a reduced Field-of-View Inversion Recovery sequence (IR-ZOOM-EPI)

Marco Battiston¹, Torben Schneider², Claudia Angela Michela Gandini Wheeler-Kingshott^1,3, and Rebecca S Samson¹

¹NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, United Kingdom, ²Philips Healthcare, Guildford, United Kingdom, ³Brain Connectivity Center, C. Mondino National Neurological Institute, Pavia, Italy

The T₁ relaxation time is a fundamental quantitative Magnetic Resonance parameter widely used to characterize healthy and pathological tissue. However, investigation of quantitative T₁ in the human spinal cord has been limited to date. In this work, we propose a scan time efficient protocol in the spinal cord for Inversion Recovery T₁ mapping, which is considered the “gold-standard” method. The mean (± standard deviation) T₁ for white matter and grey matter in the cervical spinal cord were found to be respectively 1096 (±26) ms and 1153 (±24) ms.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.