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Abstract #4423

Congenital sensorineural hearing loss affects the development of corpus callosum

Weiwei Men1, Tianbing Song2, Shuang Xia3, Yaoyu Zhang1, Jing Che4, and Jia-Hong Gao1

1Center for MRI Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of, 2Beijing cancer hospital, Beijing, China, People's Republic of, 3Tianjing First Central Hospital, Tianjing, China, People's Republic of, 4Aerospace Central Hospital, Beijing, China, People's Republic of

Congenital sensorineural hearing loss (CSHL) is a common disease in newborns, which can affect the development of corpus callosum (CC). In this study, a novel method of CC thickness analysis was employed to compare the CC difference between deaf and control groups. The results indicate that after 24 months deaf group has thinner CC thickness in the anterior splenium of CC compared to control group, which means the development of deaf anterior splenium is slowed down. Our study suggests that 12~24 month old is the best time period for CSHL treatment and intervention.

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