Abstract #4512

T2* Mapping of Lower Leg Muscles Following Single Brief Contractions at 3 T

Prodromos Parasoglou¹, Tiejun Zhao², Oleksandr Khegai¹, Xuejiao Che¹, and Jill M Slade³

¹Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Siemens Medical Solutions USA, Siemens Healthcare, New York, NY, United States, ³Department of Radiology, Michigan State University, East Lansing, MI, United States

Microvascular function in the skeletal muscle can be assessed through blood oxygenation level dependent (BOLD) MRI signal changes after performing a brief exercise or following a period of induced ischemia. Such BOLD related relaxation changes are mainly attributed to intravascular mechanisms, such as changes in the hemoglobin content and oxygen saturation levels. In this work, we developed and implemented a rapid echo-planar imaging (EPI) method to map T₂* changes, following a single maximum voluntary contraction on a 3 T whole body clinical scanner.

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