Abstract #4518

Evaluation of Cuff-Induced Skeletal Muscle Microvascular Perfusion of Lower Extremity by ASL and IVIM MRI techniques

Qing Lu¹, Shiteng Suo¹, Hui Tang¹, Jianxun Qu², Yong Zhang², and Jianrong Xu¹

¹Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, People's Republic of, ²GE Healthcare China, Shanghai, China, People's Republic of

Arterial spin labeling (ASL) and intravoxel incoherent motion (IVIM) are both noninvasive MRI techniques that offer quantitative perfusion measurements. The current study showed that the ASL perfusion decreased while the IVIM vascular volume fraction increased compared to baseline under cuff compression paradigm in the lower extremity muscle, indicating that the two MRI techniques based on two completely distinct mechanisms provide complementary tissue perfusion characteristics.

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