Abstract #0074

Mitigating the Effect of Magnetization Transfer in Magnetic Resonance Fingerprinting

Tom Hilbert^1,2,3, Tobias Kober^1,2,3, Tiejun Zhao⁴, Tobias Kai Block^5,6, Zidan Yu^5,6, Jean-Philippe Thiran³, Gunnar Krueger^2,3,7, Daniel K Sodickson^5,6, and Martijn Cloos^5,6

¹Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ²Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ³LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁴Siemens Medical Solution USA, Pittsburgh, PA, United States, ⁵New York University School of Medicine, Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York, NY, United States, ⁶Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, United States, ⁷Siemens Medical Solutions USA, Inc., Boston, MA, United States

Magnetic Resonance Fingerprinting (MRF) is a powerful technique for the quantification of relaxation parameters, and ideally provides correct estimates independent from the sequence used. In this work, we show that the quantification can be influenced by the pulse duration or, equivalently, the pulse bandwidth. This behavior, which we hypothesize to be related to magnetization transfer (MT) effects, is shown for the PnP-MRF sequence. We propose a first approach to encode MT effects in the MRF sequence and to model MT effects in the reconstruction, showing that this mitigates the bias in the resulting relaxation estimates.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.