Abstract #0146

Probing the BOLD-CVR response to progressive hypercapnia in patients with uni-lateral carotid artery occlusions

Alex Bhogal¹, Jeroen C.W. Siero^1,2, Hans Hoogduin¹, Peter R Luijten¹, Jeroen Hendrikse³, and Jill B De Vis⁴

¹Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ²Spinoza Center for Neuroimaging, Amsterdam, Netherlands, ³Radiology, University Medical Center Utrecht, Netherlands, ⁴University Medical Center Utrecht, Netherlands

We examine the BOLD-CVR response to a progressively increasing vascular stimulus between individuals with carotid artery occlusions and healthy, age/gender-matched controls. Using this paradigm, we aim to understand finer-scale interactions between impaired versus healthy cerebral hemispheres at different vascular stimulus magnitudes.

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