Meeting Banner
Abstract #0161

MB-SWIFT functional MRI during deep brain stimulation in rats

Lauri Juhani Lehto1, Djaudat Idiyatullin1, Jinjin Zhang1, Lynn Utecht1, Gregor Adriany1, Michael Garwood1, Olli Gröhn1,2, Shalom Michaeli1, and Silvia Mangia1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland

Commercial electrodes used for Deep Brain Stimulation (DBS) cause severe artefacts in conventional echo based MRI. Here we show near artefact free functional MRI during DBS in rats using Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) which allows acquisition at virtually zero-TE. MB-SWIFT showed strong responses in the somatosensory cortex while stimulating the ventromedial. The amplitude and extent of activation recorded with MB-SWIFT were similar with SE-EPI, although activation was flip angle dependent reflecting the possible influence of blood inflow. MB-SWIFT is a promising modality for fMRI in the presence of DBS leads or other severe susceptibility differences.

This abstract and the presentation materials are available to members only; a login is required.

Join Here