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Abstract #0164

Hyperpolarized Nuclear Spin Singlets. Opportunities for Polarization Storage. What Limits Their Lifetimes?

Alexej Jerschow1, Yuning Zhang1, Xueyou Duan1, Vladimir Sychrovsky2, and James Canary1

1New York University, New York, NY, United States, 2Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic

Hyperpolarization techniques have offered the prospect of higher sensitivity and fast imaging, as well as tracking of metabolism in real-time. Nuclear spin singlet states allow the storage of polarization for an extended period of time. Here we present results on the limiting factors for nuclear singlet state lifetimes, and methods by which they can be determined in organic molecules, which is important for designing appropriate contrast agents, or hyperpolarization techniques that track metabolites.

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