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Abstract #0172

Diffusion Weighted Imaging using a Dixon based Single Shot Turbo Spin Echo

Xinzeng Wang1, Holger Eggers2, Marco C. Pinho1,3, Ivan Pedrosa1,3, Robert E. Lenkinski1,3, and Ananth J. Madhuranthakam1,3

1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Philips Research, Hamburg, Germany, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Diffusion weighted imaging using single-shot turbo spin-echo (DWI-SShTSE) is increasingly used due to its robustness to geometric distortions, but often suffers from incomplete fat suppression at 3T using spectrally-selective fat suppression methods (SPIR/SPAIR etc.) in challenging areas with large field inhomogeneities. STIR can improve the fat suppression but at the expense of reduced SNR. In this work, we developed a multi-echo Dixon DWI-SShTSE sequence with shared field map between lower and higher b-values for uniform fat suppression without using image navigator and increasing scan times. We also demonstrated its robustness to the phase variations due to diffusion gradients.

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