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Abstract #0201

CEST Signals of Lipids

Steffen Goerke1, Moritz Zaiss1,2, Dario Longo3, Francesca Garello4, Enza Di Gregorio4, Johannes Breitling1, Mark E Ladd1, and Peter Bachert1

1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Department of High-field Magnetic Resonance, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany, 3Institute of Biostructure and Bioimaging, Consiglio Nazionale delle Ricerche (CNR), Turin, Italy, 4Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy

In this study, lipids were identified to be an important contributor to the upfield chemical exchange saturation transfer (CEST) signals of brain tissue. This finding can explain the pronounced CEST image contrast between gray and white matter observed in healthy volunteers.

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