Spatial distributions of the propagation patterns of cerebrospinal fluid (CSF) motion driven by cardiac pulsation and respiration were visualized using velocity waveform correlations based on asynchronous 2-dimensional phase contrast (2D-PC) imaging. These two different driving mechanisms were evaluated using spectral analysis of the velocity waveforms for 11 healthy subjects. Delay time maps and maximum correlation maps showed the spatial distribution differences between the cardiac-driven and respiratory-driven CSF motion propagations. Maximum correlation at the prepontine was 0.83±0.05 for cardiac propagation and 0.74±0.04 for respiratory propagation with a significant difference (p << 0.01). Strong propagation may not necessarily cause large CSF displacement.
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