Within-subject differences of T1, T2* and cortical thickness can be used to automatically parcellate the cortex, e.g. to guide functional analyses or increase statistical power. Here, we evaluate the additional benefit of baseline CBF as a marker for brain metabolism to differentiate regions. We demonstrate that CBF data is not redundant with the other quantitative MRI parameters. Therefore, a data-driven parcellation of brain regions that incorporates perfusion information allows delineation of the cortex into smaller units and enhances subsequent anatomical & functional analysis.