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Abstract #0366

A paradoxical systemic bias in Gd-EOB-DTPA-enhanced T1 relaxometry of the liver: a comparison of SMART1Map and MOLLI.

Akira Yamada1, Sachie Fujita1, Yoshihiro Kitoh2, Yasuo Adachi2, Hayato Hayashibara2, Aya Shiobara2, Atsushi Nozaki3, Yuji Iwadate3, Glenn S Slavin4, Yasunari Fujinaga1, and Masumi Kadoya1

1Department of Radiology, Shinshu Univ. School of Medicine, Matsumoto, Japan, 2Department of Radiology, Shinshu Univ. Hospital, Matsumoto, Japan, 3GE Healthcare Japan, Japan, 4GE Healthcare, United States

SMART1Map (saturation method using adaptive recovery times for cardiac T1 mapping) is a new single-point T1 mapping technique that directly measures true T1 unlike look-locker approaches. The feasibility of Gd-EOB-DTPA-enhanced T1 relaxometry of the liver using SMART1Map was evaluated comparing with modified look-locker inversion recovery (MOLLI). A significant paradoxical systemic bias was observed between and within SMART1Map and MOLLI in Gd-EOB-DTPA-administrated liver, although SMART1Map may be more reproducible than MOLLI in the rest of conditions. Careful consideration should be given to the effect of the paradoxical systemic bias in the evaluation of liver function using Gd-EOB-DTPA-enhanced T1 relaxometry.

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