Abstract #0528

Clinical Evaluation of Whole-Heart Quantitative Adenosine Stress CMR with Motion-compensated L1-SPIRIT

Michael Salerno¹, Yang Yang¹, Stephen McHugh¹, Eric Holland¹, Jonathan Pan², Craig H Meyer², Angela Taylor¹, and Christopher M Kramer³

¹Department of Medicine, University of Virginia, Charlottesville, VA, United States, ²Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ³Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

Adenosine stress CMR has potential advantages over competing modalities for diagnosing coronary artery disease (CAD) including the ability to quantify myocardial perfusion, however current CMR techniques have limited spatial coverage. We perform a clinical assessment of the diagnostic performance of whole-heart spiral perfusion imaging using motion compensated compressed sensing for detection of CAD and demonstrate good image quality, minimal motion artifacts, and high diagnostic accuracy for both visual and quantitative evaluation.

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