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Abstract #0529

Coronary Relaxation Mapping for Multi-fold Amplification in Myocardial BOLD Sensitivity

Hsin-Jung yang1, Damini Dey1, Behzad Sharif1, Jane Sykes2, John Butler2, Ivan Cokic1, Sotirios Tsaftaris3, Piotr Slomka1, Frank Prato2, and Rohan Dharmakumar1

1Cedars Sinai Medical Center, Los Angeles, CA, United States, 2Lawson Health Research Institute, 3IMT School for Advanced Studies Lucca

Over the past two decades cardiac BOLD MRI has seen major technical advances. However, its reliability for detecting ischemic heart disease remains poor. We hypothesized that the reliability of cardiac BOLD MRI can be improved by repeatedly acquiring BOLD images following regadenoson injection. We found that repeatedly acquired myocardial BOLD imaging following regadenoson administration can be used to significantly amplify the BOLD sensitivity and improve the reliability of myocardial BOLD MRI in health and disease.

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