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Abstract #0660

Interobserver Agreement and Diagnostic Performance of LI-RADS v2014 on contrast-enhanced MRI for non-HCC malignancies.

Natally de Souza Maciel Rocha Horvat1, Ines Nikolovski1, Niamh Long1, Scott Gerst1, Jian Zheng1, Linda Ma Pak1, Junting Zheng1, Lorenzo Mannelli1, and Richard Kinh Gian Do1

1Memorial Sloan Kettering Cancer Center, NY, NY, United States

Patients at risk for hepatocellular carcinoma (HCC) are often also at risk for intrahepatic cholangiocarcinoma (ICC) and combined hepatocellular cholangiocarcinoma (cHCC-ICC). The purpose of this study was to evaluate the sensitivity and specificity of MRI in 4 radiologists using LI-RADS v2014 and their inter-reader agreement for diagnosing non-HCC malignancies (ICC and cHCC-ICC). Applying LI-RADS v2014, we found sensitivities between 74% to 88% for the diagnosis of non-HCC malignancies with moderate to substantial interreader agreement for LI-RADS category as LR-M or non LR-M. However, lower sensitivity was seen for smaller tumors, which are known to overlap with HCC in imaging appearance.

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