Abstract #0660

Interobserver Agreement and Diagnostic Performance of LI-RADS v2014 on contrast-enhanced MRI for non-HCC malignancies.

Natally de Souza Maciel Rocha Horvat¹, Ines Nikolovski¹, Niamh Long¹, Scott Gerst¹, Jian Zheng¹, Linda Ma Pak¹, Junting Zheng¹, Lorenzo Mannelli¹, and Richard Kinh Gian Do¹

¹Memorial Sloan Kettering Cancer Center, NY, NY, United States

Patients at risk for hepatocellular carcinoma (HCC) are often also at risk for intrahepatic cholangiocarcinoma (ICC) and combined hepatocellular cholangiocarcinoma (cHCC-ICC). The purpose of this study was to evaluate the sensitivity and specificity of MRI in 4 radiologists using LI-RADS v2014 and their inter-reader agreement for diagnosing non-HCC malignancies (ICC and cHCC-ICC). Applying LI-RADS v2014, we found sensitivities between 74% to 88% for the diagnosis of non-HCC malignancies with moderate to substantial interreader agreement for LI-RADS category as LR-M or non LR-M. However, lower sensitivity was seen for smaller tumors, which are known to overlap with HCC in imaging appearance.

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