Abstract #0699

Optimization of Lateral Geniculate Nucleus Volume Determination at 3T and 7T

Njoud Aldusary^1,2, Lars Michels¹, Birgit Keisker¹, Michael Wyss³, Karen Huebel¹, Arwa Baeshen^1,2, David Otto Brunner³, Klaas Paul Pruessmann³, Klara Landau⁴, Spyridon Kollias¹, and Marco Piccirelli¹

¹Neuroradiology, University Hospital Zurich, Zurich, Switzerland, ²King Abdulaziz University, Jedaah, Saudi Arabia, ³Inst. for Biomed. Eng., University and ETH Zurich, Zurich, Switzerland, ⁴Ophthalmology, University Hospital Zurich, Zurich, Switzerland

The clinical 2D PD scans and the research very high resolution 3D T1 scans used to determine the lateral geniculate nucleus (LGN) have high contrast respectively high resolution, but too low resolution respectively too long acquisition time. Nevertheless, volumetric and contrast quantification of the LGN and of other brain tissues might increase in clinical relevance. Therefore, we optimized the contrast of 3D T1 MPRAGE to obtain the best contrast with sufficient resolution to quantify volume and contrast of the LGN.

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