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Abstract #0796

Volumetric blood flow measurement with territorial segmentation of time-resolved contrast enhanced magnetic resonance angiography of the brain

Oren Geri1,2, Shelly I. Shiran3, Jonathan Roth4, Moran Artzi1, Liat Ben-Sira3, and Dafna Ben Bashat1,2,5

1Functional Brain Center, The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, 3Department of Radiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 4Department of NeuroSurgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

We propose a method for territorial segmentation and volumetric flow rate (VFR) measurement based on time-resolved contrast enhanced MR-angiography. Eight territories: right/left internal carotid arteries; the two anterior cerebral arteries (combined); the right/left external carotid arteries; the right/left posterior cerebral arteries; and the vertebrobasilar territory, were segmented using an iterative region-growing algorithm based on the bolus-arrival-time with increased temporal resolution. VFR was measured based on the territorial volume as a function of time. Healthy subjects' VFR results were similar to literature values. The clinical potential of this method is demonstrated on one patient with Moyamoya before and after surgery.

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