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Abstract #0799

Assessment of Carotid Atherosclerotic Disease Using 3D Simultaneous Non-contrast Angiography and Intraplaque Hemorrhage (SNAP) imaging: Comparison with Digital Subtraction Angiography

Huilin Zhao1, Jianrong Xu1, Xiaosheng Liu1, Beibei Sun1, Weibo Chen2, Chun Yuan3, and Xihai Zhao4

1Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China, 2MR Clinical Science, Philips Healthcare, Greater China, People's Republic of China, 3University of Washington, WA, United States, 4Center for Biomedical Imaging Research,Department of Biomedical Engineering, Tsinghua University, Beijing, People's Republic of China

3D fast Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP) imaging was recently proposed as a technique for joint MRA and intraplaque hemorrhage (IPH) imaging. This study sought to determine the accuracy of this technique at quantifying carotid atherosclerosis disease compared to conventional intra-arterial digital subtraction angiography (DSA) in patients with at least 50% carotid stenosis. We found that 3D SNAP imaging had excellent agreement with DSA in measuring luminal stenosis and identification of ulceration in carotid arteries. Our findings suggest that, SNAP imaging might be a potential candidate technique for comprehensive evaluation of carotid high-risk atherosclerotic disease.

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