In the immunotherapy research field, establishing appropriate preclinical model is very important to evaluate the complex immune reaction. Orthotopic tumor model is more physiologic than ectopic tumor model, however its use may be limited due to difficulty in evaluating deep-seated tumors, especially in the colorectum having a complex anatomy. MR colonography (MRC) is a new technique in preclinical trial, which uses Fluorinert, a negative contrast agent, to fill the colorectum. Our study demonstrated that MRC is quite feasible to evaluate colorectal tumors and metastatic foci in orthotopic colorectal tumor model, which can be useful in immunotherapy drug development.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords