Whether Magnetization Transfer could affect Multiexponential T2 (MET2) Relaxometry remains poorly explored. Here, the effects of irradiation at different offset frequencies on the MET2 components were evaluated as novel contrast mechanisms for white matter in the rat spinal cord at 16.4T. MET2 coefficients were found to shift with off-resonance saturation, showing unique tract-specific signatures across the irradiation frequency. Offset-saturation-induced (osi-) MET2 Relaxometry maps show strong contrasts between microstructurally-distinct rat spinal cord tracts. The potential of exploiting the osi-MET2 shift phenomenon to increase white matter contrast is discussed.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords