Abstract #0999

Magneto-Caloric Materials as Tunable and Switchable Labels for MRI

Mladen Barbic¹, Tim D Harris¹, Stephen Dodd², H Douglas Morris³, Alan P Koretsky², Barbara Marcheschi⁴, Alan Huston⁴, and Neil R Dilley⁵

¹Applied Physics and Instrumentation Group, HHMI-Janelia Research Campus, Ashburn, VA, United States, ²Laboratory of Functional and Molecular Imaging, NIH/NINDS, Bethesda, MD, United States, ³NIH Mouse Imaging Facility, NIH/NINDS, Bethesda, MD, United States, ⁴Code 5611, Optical Sciences Division, Naval Research Laboratory, Washington, DC, United States, ⁵Quantum Design, Inc., San Diego, CA, United States

We present the case for the use of magneto-caloric materials as tunable and switchable labels for MRI. Sharp magnetic phase transitions these materials have at typical physiological temperatures and in the presence of the large DC magnetic field values associated with MRI machines make them uniquely suitable for the development of novel MRI contrast agents. We present physical and MRI measurements of a prototypical magneto-caloric material Iron-Rhodium (FeRh) that clearly demonstrate the MR image contrast changes due to the temperature tunable magnetic state of the material in the MRI compatible magnetic field range and physiologically relevant temperature range.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.