Abstract #1059

High resolution maps of individual macromolecule components in the human brain at 9.4T

Sahar Nassirpour^1,2, Paul Chang^1,2, and Anke Henning^1,3

¹MPI for Biological Cybernetics, Tuebingen, Germany, ²IMPRS for Cognitive and Systems Neuroscience, Eberhard Karls University of Tübingen, Tuebingen, Germany, ³Institute of Physics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

Although ultra-short TE spectroscopy sequences enhance the information content of the spectrum, they are, in their nature, prone to quantification biases if the macromolecular (MM) components are not taken into account The aim of this study, was to 1) perform macromolecule mapping at 9.4T using an ultra-short TE double-inversion recovery (DIR) MRSI sequence, 2) model and parametrize the individual MM components, and 3) extract high resolution maps of individual MM components using the modelled MM basis set.

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