Abstract #1074

Parametric mapping with spatial registration of abdominal MRI is feasible and may inform upon the spatial distribution of fibrosis in intestinal lesions of patients with Crohn’s Disease

Elizabeth Li¹, Jordi Rimola, MD PhD², Timothy Lu, MD¹, Alexandre Coimbra, PhD¹, and Alex De Crespigny, PhD¹

¹Genentech Inc, South San Francisco, CA, United States, ²Department of Radiology, Hospital Clínic de Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain

Parametric mapping may provide estimates of the degree and spatial distribution of fibrosis in Crohn’s Disease (CD) patients but is subject to respiratory and peristaltic motion. Validation of out-of-the-box registration strategies and their impact on quality and robustness of parametric maps-delayed gain of enhancement (DGE) and magnetization transfer ratio (MTR) were evaluated.

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