Abstract #1164

Management of complex regional pain syndrome (CRPS) with [18F]FTC-146 PET/MRI

Daehyun Yoon¹, Peter Cipriano¹, Trine Hjoernevik^1,2,3, Bin Shen¹, Dawn Holley¹, Harsh Gandhi¹, Vivianne Tawfik⁴, Catherine Curtin⁵, Ian Carroll⁴, Christopher McCurdy⁶, Brian Hargreaves¹, Frederick Chin¹, and Sandip Biswal¹

¹Department of Radiology, Stanford university, Palo Alto, CA, United States, ²The Intervention Centre, Oslo University Hospital, Oslo, Norway, ³The Norwegian Medical Cyclotron Centre, Oslo, Norway, ⁴Department of Anesthesiology, Stanford university, Palo Alto, CA, United States, ⁵Department of Surgery, Stanford university, Palo Alto, CA, United States, ⁶Department of BioMolecular Sciences, The University of Mississippi

Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition affecting millions of patients worldwide. However, no specific diagnosis is currently available to accurately detect the pain generators in CRPS, and thus successful pain management for CRPS is very challenging. In this abstract, we propose a PET/MRI approach with a novel pain-specific PET tracer for identifying pain generators in CRPS. Our early experience with the proposed PET/MRI approach demonstrates that the image findings could alter the pain management for CRPS patients to achieve better pain-relief outcome.

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