Visual cortex functionality in the blind has been shown to shift away from sensory networks toward task-positive networks that are involved in top-down modulation. However, how such modulation is shaped by experience and reflected behaviorally remains unclear. Using blood-oxygenation-level-dependent functional MRI with a sensory substitution task, we found that top-down visual cortex activity negatively correlates with duration of blindness and reaction time. Our results suggest that alterations in top-down brain activity due to visual deprivation progress as a function of time. Furthermore, the degree of top-down activity in the visual cortex may reflect the speed of performance during sensory substitution.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords