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Abstract #1382

Stacked Frequency Wave Inversion (SFWI): Heterogeneous And Edge-Preserving Direct Inversion For Magnetic Resonance Elastography (MRE)

Eric Barnhill1, Monika Bahl2, Florian Dittmann1, Sebastian Hirsch1, Jürgen Braun3, and Ingolf Sack1

1Radiological Science, Charité Universitätsmedizin Berlin, Berlin, Germany, 2Physics, Indian Institute of Technology Delhi, New Delhi, India, 3Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany

A new reconstruction method for MR elastography exploits a recent finding of mathematical uniqueness to develop a heterogeneity-accommodating and edge-preserving direct inversion method that uses first order derivatives. We investigate this new method on FEM models and a cohort of in vivo brain acquisitions by comparing it with a previously published method known as ESP. In models the method removes artefacts from use of second derivatives and homogeneity assumptions. In brain images appear better conditioned, but shows values differing from ESP in more anisotropic brain regionss.

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