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Abstract #1535

The effect of loading on T2* and MT ratio in tendons: A feasibility study

Saeed Jerban1, Amin Nazaran1, Michael Carl2, Xin Cheng1, Eric Y Chang1,3, and Jiang Du1

1Radiology, University of California, San Diego, San Diego, CA, United States, 2GE Healthcare, San Diego, CA, United States, 3Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

UTE_MRI is assumed to be a great non-invasive technique to assess tendons as a unique viscoelastic tissue, with a very short T2. Early stage of tendon diseases, is hypothesized to affect the mechanical properties of tendon sooner and quicker than its morphology. This study, focused on the UTE-based T2* and MTR variations of the tendon samples under mechanical loading. Stretching the tendon samples with different loads using an MRI-compatible device resulted in significant reductions of T2* and increases in MTR. The MTR regional variations and shifts, obtainable by presented approach will help for assessing tendon quality and health level.

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