Abstract #1917

Quantification of tracer kinetic and hemodynamic parameters of human breast tumor and fibro-glandular tissue using DCE-MRI data

Snekha Sehrawat¹, Pradeep Kumar Gupta ², Meenakshi Singhal², Rakesh Kumar Gupta², and Anup Singh^1,3

¹Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Delhi, India, ²Fortis Memorial Research Institute, Gurgaon, India, Delhi, India, ³Department for Biomedical Engineering, AIIMS Delhi, New Delhi, India.

Objective of current study was to develop a framework for computing tracer kinetic parameters using GTKM model and hemodynamic parameters using first pass analysis of human breast tissue for characterizing of breast lesion; and also differentiation of the histological grade II and III of breast cancer. A significant difference between benign, malignant and fibroglandular tissues; and also between grade II and III of breast cancer were observed.

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