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Abstract #1928

Relaxation time shortening by oxygen molecules: Strong enhancement in a viscous solution with cellular viscosity

Masayuki Taguchi1 and Toru Yamamoto2

1Graduate School of Health Sciences, Hokkaido University, sapporo, Japan, 2Faculty of Health Sciences, Hokkaido University, sapporo, Japan

Since oxygen molecules are paramagnetic, they shorten the relaxation time as well as gadolinium contrast medium. The effect of relaxation time shortening by the paramagnetic substance is enhanced with an increase in viscosity of the solution as in the cell. We investigated the longitudinal and transverse relaxivities of oxygen in viscous solution with cellular viscosity and clarified that the relaxation time shortening by oxygen molecules strongly increases with an increase in viscosity. This effect of oxygen in the cell may be visible by using pulse sequences that enhance the signal from the cellular proton.

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