MRI is increasingly being used in post-mortem examinations to assist in determining cause of death. Post-mortem changes, such as the formation of post-mortem clots (PMC), present a specific challenge in forensic imaging where differentiation between these alterations and pathological findings (e.g. thromboemboli) is essential. This work imaged thromboemboli and PMC samples collected during autopsy at 3T. K-means clustering was applied to analyse voxel-grouping in the resulting quantitative data. Clusters specific to a single clot type were identified in 3 of the 4 samples. Preliminary findings indicated the existence of at least one common differentiating cluster specific to PMC.