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Abstract #1941

Cause of death or caused by death: Differentiation of thromboemboli and post-mortem clots using quantitative MRI

Bridgette Webb1,2, Martin Urschler1,2, Marlene Leoni3, Bernhard Neumayer1,2, Thomas Widek1,2, Sylvia Scheicher1,2, Rudolf Stollberger2,4, and Thorsten Schwark1,5

1Ludwig Boltzmann Institute for Clinical Forensic Imaging, Graz, Austria, 2BioTechMed, Graz, Austria, 3Institute of Pathology, Medical University Graz, Graz, Austria, 4Institute of Medical Engineering, Graz University of Technology, Graz, Austria, 5Institute of Forensic Medicine, Medical University Graz, Graz, Austria

MRI is increasingly being used in post-mortem examinations to assist in determining cause of death. Post-mortem changes, such as the formation of post-mortem clots (PMC), present a specific challenge in forensic imaging where differentiation between these alterations and pathological findings (e.g. thromboemboli) is essential. This work imaged thromboemboli and PMC samples collected during autopsy at 3T. K-means clustering was applied to analyse voxel-grouping in the resulting quantitative data. Clusters specific to a single clot type were identified in 3 of the 4 samples. Preliminary findings indicated the existence of at least one common differentiating cluster specific to PMC.

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