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Abstract #1942

An optimised 2D MPRAGE sequence for T1 contrast in the fetal brain: application to slice to volume reconstruction and multiband acceleration

Giulio Ferrazzi1, Anthony N. Price1, Rui Pedro AG Teixeira1, Francesco Padormo2, Lucilio Cordero-Grande1, Emer Hughes1, Laura McCabe1, Mary Rutherford1, Maria Kuklisova Murgasova1, and Joseph V. Hajnal1

1Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom, 2Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, United States

Ultrafast single-shot T2 weighted images are common practise in fetal MR exams. However, there is limited experience with fetal T1 acquisitions.

In this study, a 2D gradient echo sequence with an adiabatic inversion was optimized to be robust to fetal motion and to preserve contrast. We also explore slice to volume registration and super resolution reconstruction methods to enhance the resolution, and we show pilot data from a multiband accelerated version of the above-mentioned sequence.

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