Chemical exchange rotation transfer (CERT) is an emerging approach for imaging solutes and solute exchange that avoids some of the contributions from the asymmetric background in biological tissues that confound chemical exchange saturation transfer (CEST). To further improve the robustness of CERT methods when there is field inhomogeneity, we examined adiabatic hyperbolic secant pulses for solute saturation. In addition to addressing field homogeneity issues, this new method reveals a new mechanism to generate contrast based on the delay time between pulse.
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