A novel concentration-independent approach is presented to determine the pH-dependence of exchange rates employing a single CEST image of a set of model solutions at different pH. Not only the comparatively short acquisition time, but also the robustness against variations in relaxation parameters makes this modality an elegant way to determine exchange rates in vitro. The calibrated functions are required for accurate pH mapping in vivo using CEST, as well as for design of exogenous CEST contrast agents.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords