We propose a use of sinc-modulated RF pulse train instead of the conventional continuous wave RF irradiation under the presence of constant gradient as a saturation scheme in chemical exchange saturation transfer (CEST) MRI aiming at a simultaneous acquisition of multiple Z-spectra. The proposed method was applied for a glutamic acid solution in water. The multiple Z-spectra could be observed along the gradient encoding direction by repetitive application of the saturation scheme. Thus, the present study shows the potential of the proposed methodology for accelerating the CEST MRI.
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