Meeting Banner
Abstract #2138

3D Mapping of Whole Lung Morphometry with 129Xe Diffusion-Weighted MRI and Compressed Sensing: Comparison with 3He

Ho-Fung Chan1, Neil J Stewart1, Juan Parra-Robles1,2, Guilhem J Collier1, and Jim M Wild1

1Academic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom, 2Department of Bioengeering, Universidad Carlos III de Madrid, Madrid, Spain

3D whole lung morphometry maps were acquired with 129Xe DW-MRI and compressed sensing. Prospective three-fold undersampled 3D 129Xe lung morphometry (LmD) maps were derived using the stretched exponential model (SEM) and compared with equivalent 3He datasets. Five healthy volunteers were imaged using a range of 129Xe diffusion times and the most agreeable 129Xe and 3He LmD results were obtained with a 129Xe diffusion time of 8.5 ms. These results indicate that the LmD values derived from the SEM are dependent on diffusion time and that 129Xe could present a clinically-viable alternative to 3He for whole lung morphometry mapping.

This abstract and the presentation materials are available to members only; a login is required.

Join Here